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・ Phosphorescent organic light-emitting diode
・ Phosphoria Formation
・ Phosphoribokinase
・ Phosphoribosyl pyrophosphate
・ Phosphoribosyl-AMP cyclohydrolase
・ Phosphoribosyl-ATP diphosphatase
・ Phosphoribosyl-N-formylglycineamide
・ Phosphoribosylamine
・ Phosphoribosylamine—glycine ligase
・ Phosphoribosylaminoimidazole carboxylase
・ Phosphoribosylaminoimidazole synthetase
・ Phosphoribosylaminoimidazolecarboxamide formyltransferase
・ Phosphoribosylaminoimidazolesuccinocarboxamide
・ Phosphoribosylaminoimidazolesuccinocarboxamide synthase
・ Phosphoribosylanthranilate isomerase
Phosphoribosylformylglycinamidine synthase
・ Phosphoribosylglycinamide formyltransferase
・ Phosphoribosyltransferase
・ Phosphoribulokinase
・ Phosphoric
・ Phosphoric acid
・ Phosphoric acid fuel cell
・ Phosphoric acids and phosphates
・ Phosphoric monoester hydrolases
・ Phosphorine
・ Phosphorite
・ Phosphorite War
・ Phosphorolysis
・ Phosphoroscope
・ Phosphorous


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Phosphoribosylformylglycinamidine synthase : ウィキペディア英語版
Phosphoribosylformylglycinamidine synthase

In enzymology, a phosphoribosylformylglycinamidine synthase () is an enzyme that catalyzes the chemical reaction
:ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O \rightleftharpoons ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate
The 4 substrates of this enzyme are ATP, N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide, L-glutamine, and H2O, whereas its 4 products are ADP, phosphate, 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine, and L-glutamate.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming). Other names in common use include phosphoribosylformylglycinamidine synthetase, formylglycinamide ribonucloetide amidotransferase, phosphoribosylformylglycineamidine synthetase, FGAM synthetase, FGAR amidotransferase, 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase, (ADP-forming), 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine, and amido-ligase (ADP-forming). This enzyme participates in purine metabolism.
==Structural studies==

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , and .

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